Authors from the Luo Lab are marked with ^, first authors marked with #, and corresponding authors marked with *.

Chai, G. S.#^, Chen, H. X.^, Ma, D. Z.^, Ren, Z. H.^, Liu, X. H.^, Luo, G. Z.^* (2024). Comprehensive analysis across mammalian tissues and cells decipher the underlying mechanism of m6A specificity. bioRxiv. [In preprint]
PMID: 3 DOI: 10.1101/2024.04.19.590363 Luo Lab authors: Guoshi Chai, Hongxuan Chen, Dongzhao Ma, Zehui Ren, Xuehong Liu, Guanzheng Luo,

Xie, Y. Y.#^, Zhong, Z. D.#^, Chen, H. X.#^, Qiu, Y. T.^, Ren, Z. H.^, Lan, Y. L.^, Wu, F.^, Kong, J. W.^, Luo, R. J.^, Zhang, D., Liu, B. D.^, Shu, Y.^, Yin, F., Wu, J., Li, Z., Zhang, Z.*^, Luo, G. Z.*^ (2023). Single-Molecule Direct RNA Sequencing Reveals the Shaping of Epitranscriptome Across Multiple Species. bioRxiv. [In preprint]
PMID: 1 DOI: 10.1101/2023.11.16.567334 Luo Lab authors: Yingyuan Xie, Zhendong Zhong, Hongxuan Chen, Yuantao Qiu, Zehui Ren, Yelin Lan, Fu Wu, Jinwen Kong, Rujia Luo, Biaodi Liu, Yang Shu, Zhang Zhang, Guanzheng Luo,

Xi, J. F.#^, Liu, B. D.#^, Tang, G. R.#^, Ren, Z. H.^, Chen, H. X.^, Lan, Y. L.^, Yin, F., Li, Z., Cheng, W. S., Wang, J., Chen, L., Yuan, S. C., Zhang, Z.^, Luo, G. Z.*^ (2025). m6A modification regulates cell proliferation via reprogramming the balance between glycolysis and pentose phosphate pathway. Communications Biology, 8(1): 496.
PMID: 6 DOI: 10.1038/s42003-025-07937-9 Luo Lab authors: Jianfei Xi, Biaodi Liu, Guorun Tang, Zehui Ren, Hongxuan Chen, Yelin Lan, Zhang Zhang, Guanzheng Luo,

Lu, P., Deng, D., Li, X., Niu, X., Qiu, Y., Liang, Y., Liang, Y., Tang, G.^, Yuan, Z., Luo, G.^, Kennedy, S. & Wan, G.* (2025).A nuclear pore-anchored condensate enables germ granule organization and transgenerational epigenetic inheritance.Nat Struct Mol Biol (2025).
PMID: 40082670 DOI: 10.1038/s41594-025-01515-7 Luo Lab authors: Guorun Tang, Guanzheng Luo,

Li, Z. K.#, Wang, L. B.#, Wang, L. Y.#, Sun, X. H.#, Ren, Z. H.#^, Ma, S. N.#, Zhao, Y. L.#, Liu, C., Feng, G. H., Liu, T., Pan, T. S., Shan, Q. T., Xu, K., Luo, G. Z.*^, Zhou, Q.*, Li, W.* (2025). Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals. Cell Stem Cell, S1934-5909(25)00005-0.
PMID: 39879989 DOI: 10.1016/j.stem.2025.01.005. Luo Lab authors: Zehui Ren, Guanzheng Luo,

Tang H.#, Shao J#^., Jiang X., Yan W., Luo G.*^, Weng X.*(2024). Detection and site-specific editing of RNA modifications. SCIENTIA SINICA Chimica.
PMID: 5 DOI: 10.1360/SSC-2024-0244 Luo Lab authors: Jingyi Shao, Guanzheng Luo,

Wang Y.#, Wang Z., Chen W., Ren Z. H.^, Gao H., Dai J., Luo G. Z.^, Wu Z.*, Ji Q.*(2024). A KDPG sensor RccR governs Pseudomonas aeruginosa carbon metabolism and aminoglycoside antibiotic tolerance. Nucleic Acids Research, 52(2): 967-976.
PMID: 38096062 DOI: 10.1093/nar/gkad1201 Luo Lab authors: Zehui Ren, Guanzheng Luo,

Guo, X.#, Zhou, J.#, Yan, L.#, Liu, X., Yuan, Y., Ye, J., Zhang, Z., Chen, H., Ma, Y., Zhong, Z.^, Luo, G.^, Chen, H.* (2024). Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration. Developmental Cell, 59(22): 3008-3024. e8.
PMID: 39047737 DOI: 10.1016/j.devcel.2024.06.020 Luo Lab authors: Zhendong Zhong, Guanzheng Luo,

Ge, Y.#, Chen, R.#, Ling, T., Liu, B.^, Huang, J., Cheng, Y., Lin, Y., Chen, H.^, Xie, X., Xia, G., Luo, G.^, Yuan, S.*, Xu, A.*(2024). Elevated WTAP promotes hyperinflammation by increasing m 6 A modification in inflammatory disease models. The Journal of Clinical Investigation, 134(14).
PMID: 39007267 DOI: 10.1172/JCI177932 Luo Lab authors: Biaodi Liu, Hongxuan Chen, Guanzheng Luo,

Luo, R. J.#^, Chen, H. X.^, Kong, J. W.^, Zhang, Z.^, Ayoub, N., Luo, G. Z.*^(2024). Discovery and Accurate Detection of Rare Nucleic Acid Modifications. Israel Journal of Chemistry, 64(5): e202400024.
PMID: 2 DOI: 10.1002/ijch.202400024 Luo Lab authors: Rujia Luo, Hongxuan Chen, Jinwen Kong, Zhang Zhang, Guanzheng Luo,

Xu, H.#, You, H.#, Gong, J.#, Zhang, Y.#^, Du, J., Wang, X., Gu, S., Cao, N*. Wang J*. (2023) Discovery of Zidovudine as a cardiomyocyte protectant for doxorubicin-induced toxicity through high-throughput phenotypic drug screening, Fundamental Research
PMID: 0 DOI: 10.1016/j.fmre.2023.10.010 Luo Lab authors: Ying Zhang,

Liu, X. H.#^, Liu, Z.#, Ren, Z. H.^, Chen, H. X.^, Zhang, Y.^, Zhang, Z.*^, Cao, N.*, Luo, G. Z.*^(2023). Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation. Epigenetics & Chromatin, 16(1): 1-13.
PMID: 37568210 DOI: 10.1186/s13072-023-00506-6 Luo Lab authors: Xuehong Liu, Zehui Ren, Hongxuan Chen, Ying Zhang, Zhang Zhang, Guanzheng Luo,

Zhong, Z. D.#^, Xie, Y. Y.#^, Chen, H. X.^, Lan, Y. L.^, Liu, X. H.^, Ji, J. Y.^, Wu, F.^, Jin, L., Chen, J., Mak, D. W., Zhang, Z.*^, Luo, G. Z.*^(2023). Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing. Nature Communications, 14(1): 1906.
PMID: 37019930 DOI: 10.1038/s41467-023-37596-5 Luo Lab authors: Zhendong Zhong, Yingyuan Xie, Hongxuan Chen, Yelin Lan, Xuehong Liu, Jingyun Ji, Fu Wu, Zhang Zhang, Guanzheng Luo,

Liu, J.#, Zuo, H.#, Wang, Z.#, Wang, W., Qian, X., Xie, Y.^, Peng, D., Xie, Y., Hong, L., You, W., Lou, H., Luo, G.^, Ren, J., Shen, B., Zheng, J.*, Wang, H.*, Ju, Z.*(2023). The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K-Akt-mTOR signalling. Cell Proliferation, 2023:e13410.
PMID: 36722312 DOI: 10.1111/cpr.13410 Luo Lab authors: Yingyuan Xie, Guanzheng Luo,

Xu, H.#, Liu, G.#, Gong, J.#, Zhang, Y.#^, Gu, S.#, Wan, Z., Yang, P., Nie, Y., Wang, Y., Huang, Z. P., Luo, G.^, Chen, Z.*, Zhang, D.*, Cao, N*. Investigating and Resolving Cardiotoxicity Induced by COVID-19 Treatments using Human Pluripotent Stem Cell-Derived Cardiomyocytes and Engineered Heart Tissues. (2022) Adv Sci (Weinh), 9(30): e2203388.
PMID: 36055796 DOI: 10.1002/advs.202203388 Luo Lab authors: Ying Zhang, Guanzheng Luo,

Chen, L. Q.#^, Zhang, Z.#^, Chen, H. X.^, Xi, J. F.^, Liu, X. H.^, Ma, D. Z.^, Zhong, Y. H.^, Ng, W. H.^, Chen, T.^, Mak, D. W., Chen, Q., Chen, Y. Q. and Luo, G. Z.*^(2022). High-precision mapping reveals rare N6-deoxyadenosine methylation in the mammalian genome. Cell Discovery, 8(1), 1-11.
PMID: 36575183 DOI: 10.1038/s41421-022-00484-1 Luo Lab authors: Liqian Chen, Zhang Zhang, Hongxuan Chen, Jianfei Xi, Xuehong Liu, Dongzhao Ma, Yuhao Zhong, Tao Chen, Guanzheng Luo,

Zhang, M.#, Zeng, Y. P., Peng, R., Dong, J., Lan, Y. L.^, Duan, S. J., Chang, Z. Y., Ren, J., Luo, G. Z.^, Liu, B., Růžička, K., Zhao, K. W., Wang, H. B.*, Jin, H. L.*(2022). N6-methyladenosine RNA modification regulates photosynthesis during photodamage in plants. Nature Communication, 13(1), 1-19.
PMID: 36460653 DOI: 10.1038/s41467-022-35146-z Luo Lab authors: Yelin Lan, Guanzheng Luo,

Li, Y.#^, Zhi, S.#, Wu, T.#, Chen, H. X.^, Kang, R., Ma, D. Z.^, Songyang, Z., He, C.*, Liang, P*. and Luo, G. Z.*^ (2022). Systematic identification of CRISPR off-target effects by CROss-seq. Protein & Cell.
PMID: 37084235 DOI: 10.1093/procel/pwac018 Luo Lab authors: Yan Li, Hongxuan Chen, Dongzhao Ma, Guanzheng Luo,

Chen, HX^, Zhang, Z^, Ma, DZ^, Chen, LQ^, Luo, GZ^*. Mapping single-nucleotide m6A by m6A-REF-seq[J]. Methods, 2022, 203: 392-398.
PMID: 34174388 DOI: 10.1016/j.ymeth.2021.06.013 Luo Lab authors: Hongxuan Chen, Zhang Zhang, Dongzhao Ma, Liqian Chen, Guanzheng Luo,

Zhang, Z.#^, Chen, T.#^, Chen, H. X.^, Xie, Y. Y.^, Chen, L. Q.^, Zhao, Y. L.^, Liu, B. D.^, Jin, L., Zhang, W., Liu, C., Ma, D. Z.^, Chai, G. S.^, Zhang, Y.^, Zhao, W. S.^, Ng, W. H., Chen, J., Jia, G., Yang, J. and Luo, G. Z.*^ (2021). Systematic calibration of epitranscriptomic maps using a synthetic modification-free RNA library. Nat Methods 18, 1213-1222.
PMID: 34594034 DOI: 10.1038/s41592-021-01280-7 Luo Lab authors: Zhang Zhang, Tao Chen, Hongxuan Chen, Yingyuan Xie, Liqian Chen, Yuli Zhao, Biaodi Liu, Dongzhao Ma, Guoshi Chai, Ying Zhang, Wenshuo Zhao, Guanzheng Luo,

Chen, T.#^, Li, Y.#^, Ma, D.Z.^, Zhang, Z.^, Xi, J.F.^, and Luo, G.Z.* (2021). Establishment of Transposase-assisted Low-input m(6)A Sequencing Technique. J Genet Genomics.
PMID: 34474182 DOI: 10.1016/j.jgg.2021.08.007 Luo Lab authors: Tao Chen, Yan Li, Dongzhao Ma, Zhang Zhang, Jianfei Xi, Guanzheng Luo,

Chen, W.#, Ren, Z.H.#^, Tang, N., Chai, G.^, Zhang, H., Zhang, Y., Ma, J., Wu, Z., Shen, X., Huang, X., Luo, G.Z.*^, Ji Q.J.* (2021). Targeted genetic screening in bacteria with a Cas12k-guided transposase. Cell Rep 36, 109635.
PMID: 34469724 DOI: 10.1016/j.celrep.2021.109635 Luo Lab authors: Zehui Ren, Guoshi Chai, Guanzheng Luo,

Zhou F#, Liu B#, Liu X, Li Y, Wang L, Huang J, Luo G*, Wang X*. The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis. Metabolites. 2021 May 6;11(5):298
PMID: 34066348 DOI: 10.3390/metabo11050298 Luo Lab authors: Biaodi Liu, Guanzheng Luo,

Liu J, Gao M, He J, Wu K, Lin S, Jin L, Chen Y, Liu H, Shi J, Wang X, Chang L, Lin Y, Zhao YL, Zhang X, Zhang M, Luo GZ, Wu G, Pei D, Wang J, Bao X, Chen J. The RNA m 6 A reader YTHDC1 silences retrotransposons and guards ES cell identity. Nature. 2021 Mar;591(7849):322-326.
PMID: 33658714 DOI: 10.1038/s41586-021-03313-9 Luo Lab authors: Yuli Zhao, Guanzheng Luo,

Chen X#, Zhao Q#, Zhao YL#, Chai GS, Cheng W, Zhao Z, Wang J*, Luo GZ*, Cao N*. Targeted RNA N6-Methyladenosine Demethylation Controls Cell Fate Transition in Human Pluripotent Stem Cells. Advanced Science (Weinh). 2021 Jun;8(11):e2003902
PMID: 34105279 DOI: 10.1002/advs.202003902 Luo Lab authors: Yuli Zhao, Guoshi Chai, Guanzheng Luo,

Wang, M.#, Xiao, Y.#, Li, Y.#^, Wang, X., Qi, S., Wang, Y., Zhao, L., Wang, K., Peng, W., Luo, G.Z.*^, Xue, X.F.*, Jia, G.F.*, Wu, L.M.* (2021). RNA m6A Modification Functions in Larval Development and Caste Differentiation in Honeybee (Apis mellifera). Cell reports 34, 108580.
PMID: 33406439 DOI: 10.1016/j.celrep.2020.108580 Luo Lab authors: Yan Li, Guanzheng Luo,

Chen LQ#^, Zhao WS^, Luo GZ*^. Mapping and editing of nucleic acid modifications. Computational and Structural Biotechnology Journal. 18:661-667 (2020).
PMID: 32257049 DOI: 10.1016/j.csbj.2020.03.010 Luo Lab authors: Liqian Chen, Wenshuo Zhao, Guanzheng Luo,

Du G, Xiong L, Li X, Zhuo Z, Zhuang X, Yu Z, Wu L, Xiao D, Liu Z, Jie M, Liu X^, Luo G^, Guo Z, Chen H. Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair. Developmental Cell. (20)30186-6 (2020).
PMID: 32243783 DOI: 10.1016/j.devcel.2020.03.002 Luo Lab authors: Xuehong Liu, Guanzheng Luo,

Weng X, Gong J, Chen Y, Wu T, Wang F, Yang S, Yuan Y, Luo G^, Chen K, Hu L, Ma H, Wang P, Zhang QC, Zhou X, He C. Keth-seq for transcriptome-wide RNA structure mapping. Nature Chemical Biology. doi: 10.1038/s41589-019-0459-3 (2020).
PMID: 32015521 DOI: 10.1038/s41589-019-0459-3 Luo Lab authors: Guanzheng Luo,

Zhang Z#^, Chen LQ^, Zhao YL^, Yang CG, Roundtree I, Zhang Z, Ren J, Xie W, He C, Luo GZ*^. Single-base mapping of m6A by an antibody-independent method. Science Advances. 5(7):eaax0250 (2019)
PMID: 31281898 DOI: 10.1126/sciadv.aax0250 Luo Lab authors: Zhang Zhang, Liqian Chen, Yuli Zhao, Guanzheng Luo,

Lin X#, Chai G#^, Wu Y#, Li J, Chen F, Liu J, Luo G^, Tauler J, Du J, Lin S, He C, Wang H*. RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. Nature Communications. 10: 2065 (2019)
PMID: 31061416 DOI: 10.1038/s41467-019-09865-9 Luo Lab authors: Guoshi Chai, Guanzheng Luo,

Liu J#, Luo G#^, Sun J, Men L, Ye H, He C, Ren D*. METTL14 is essential for β-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 1865(9):2138-2148 (2019)
PMID: 31029827 DOI: 10.1016/j.bbadis.2019.04.011 Luo Lab authors: Guanzheng Luo,

Zhang LS#, Liu C, Ma H, Dai Q, Sun HL, Luo G^, Zhang Z, Zhang L, Hu L, Dong X, He C*. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Molecular Cell. 74(6):1304-1316 (2019)
PMID: 31031084 DOI: 10.1016/j.molcel.2019.03.036 Luo Lab authors: Guanzheng Luo,

Wang X#, Li Y#^, Chen W, Shi H, Eren AM, Morozov A, He C, Luo GZ*^, Pan T*. Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Research. 29(2):167-170 (2019)
PMID: 30559439 DOI: 10.1038/s41422-018-0127-2 Luo Lab authors: Yan Li, Guanzheng Luo,

Chen Z#, Qi M, Shen B, Luo G^, Wu Y, Li J, Lu Z, Zheng Z, Dai Q, Wang H*. Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs. Nucleic Acids Research. 47(5):2533-2545 (2019)
PMID: 30541109 DOI: 10.1093/nar/gky1250 Luo Lab authors: Guanzheng Luo,

Luo GZ#*^, Hao Z#, Luo L, Shen M, Sparvoli D, Zheng Y, Zhang Z, Weng X, Chen K, Cui Q, Turkewitz AP and He C*. N6-methyldeoxyadenosine directs nucleosome positioning in Tetrahymena DNA. Genome Biology. 19:200 (2018)
PMID: 30454035 DOI: 10.1186/s13059-018-1573-3 Luo Lab authors: Guanzheng Luo,