Published on Feb. 20, 2020, by Admin in the Luo Lab
By cooperating with Dr. Wang Hongsheng from the School of Pharmaceutical Sciences, Sun Yat-sen University, Guoshi published this paper in Nature Communications as a co-first author.
N6-Methyladenosine (m6A) modification has been implicated in the progression of several cancers. The article, titled RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail, reveals a significant increase of m6A levels in cancer cells undergoing epithelial-mesenchymal transition (EMT), highlighting the critical roles of m6A on regulation of EMT in cancer cells and translation of Snail, a key transcription factor of EMT, with compelling in vitro and in vivo evidences provided. Congratulations!