Hongxuan Chen

PhD Candidate
Biochemistry and Molecular Biology, Sun Yat-sen University
M.S., Bioengineering, Sun Yat-sen University
B.S., Chemistry, Hunan University

E-mail: chenhongxuan1997@icloud.com

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Research and Scholarly Interests

Mechanism and detection of epigenetic modifications.

Publications

Authors from the Luo Lab are marked with ^, first authors marked with #, and corresponding authors marked with *.

Xie Y. Y.#^, Zhong Z. D.#^, Chen H. X.#^, Lan, Y. L.^, Wu, F.^, Kong, J. W.^, Luo, R. J.^, Liu, B. D.^, Shu, Y.^, Yin, F., Li, Z., Zhang, Z.*^, Luo, G. Z.^* (2023). Single-Molecule Direct RNA Sequencing Reveals the Shaping of Epitranscriptome Across Multiple Species. bioRxiv. [In preprint]
DOI: 10.1101/2023.11.16.567334

Liu, X. H.#^, Liu, Z.#, Ren, Z. H.^, Chen, H. X.^, Zhang, Y.^, Zhang, Z.*^, Cao, N.*, Luo, G. Z.*^(2023). Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation. Epigenetics & Chromatin, 16(1): 1-13.
PMID: 37568210 DOI: 10.1186/s13072-023-00506-6

Zhong, Z. D.#^, Xie, Y. Y.#^, Chen, H. X.^, Lan, Y. L.^, Liu, X. H.^, Ji, J. Y.^, Wu, F.^, Jin, L., Chen, J., Mak, D. W., Zhang, Z.*^, Luo, G. Z.*^(2023). Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing. Nature Communications, 14(1): 1906.
PMID: 37019930 DOI: 10.1038/s41467-023-37596-5

Chen, L. Q.#^, Zhang, Z.#^, Chen, H. X.^, Xi, J. F.^, Liu, X. H.^, Ma, D. Z.^, Zhong, Y. H.^, Ng, W. H.^, Chen, T.^, Mak, D. W., Chen, Q., Chen, Y. Q. and Luo, G. Z.*^(2022). High-precision mapping reveals rare N6-deoxyadenosine methylation in the mammalian genome. Cell Discovery, 8(1), 1-11.
PMID: 36575183 DOI: 10.1038/s41421-022-00484-1

Li, Y.#^, Zhi, S.#, Wu, T.#, Chen, H. X.^, Kang, R., Ma, D. Z.^, Songyang, Z., He, C.*, Liang, P*. and Luo, G. Z.*^ (2022). Systematic identification of CRISPR off-target effects by CROss-seq. Protein & Cell.
PMID: 37084235 DOI: 10.1093/procel/pwac018

Zhang, Z.#^, Chen, T.#^, Chen, H. X.^, Xie, Y. Y.^, Chen, L. Q.^, Zhao, Y. L.^, Liu, B. D.^, Jin, L., Zhang, W., Liu, C., Ma, D. Z.^, Chai, G. S.^, Zhang, Y.^, Zhao, W. S.^, Ng, W. H., Chen, J., Jia, G., Yang, J. and Luo, G. Z.*^ (2021). Systematic calibration of epitranscriptomic maps using a synthetic modification-free RNA library. Nat Methods 18, 1213-1222.
PMID: 34594034 DOI: 10.1038/s41592-021-01280-7

Chen HX, Zhang Z, Ma DZ, Chen LQ, Luo GZ. Mapping single-nucleotide m6A by m6A-REF-seq. Methods. S1046-2023(21)00175-4. (2021)
PMID: 34174388 DOI: 10.1016/j.ymeth.2021.06.013