Guanzheng Luo

Professor
Ph.D., Bioinformatics
B.S., Biomedical Engineering

  • 2020- , PI, State Key Laboratory of Biocontrol, Sun Yat-sen University
  • 2017- , PI, MOE Key Laboratory of Gene Function and Regulation, Sun Yat-sen University
  • 2017- , Tenure-track Professor, School of Life Sciences, Sun Yat-sen University
  • 2013-2017, Postdoctoral fellow, Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago
  • 2010-2013, Research assistant, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
  • 2005-2010, Ph.D., Bioinformatics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
  • 2001-2005, B.S., Biomedical Engineering, Southeast University

E-mail: luogzh5@mail.sysu.edu.cn

photo
Research and Scholarly Interests

Epigenetics, Genomics, Bioinformatics, Synthetic Biology, High-throughput Sequencing, Nucleotide Modification

Teaching

Molecular Biology , Undergraduate students , 2019-present

Scientific writing , Undergraduate students , 2019-present

Precision medicine , Undergraduate students , 2018-2019

Funding

Nucleic acid modification and gene expression , NSFC , National Science Fund for Excellent Young Scholars , 2020-2022

Regulation of gene expression by DNA N6-methyladenine assisted nucleosome positioning , NSFC , General Program , 2019-2022

Characterization of DNA 6mA in early embryonic development , NSFC , Major Research Plan , 2018-2020

Publications

Authors from the Luo Lab are marked with ^, first authors marked with #, and corresponding authors marked with *.

2025

Zhang, Y.#^, Zhang, Z. Y.#^, Chen, H. X.#^, Liu, C., Liu, B. D.^, Lan, Y. L.^, Xie, Y. Y.^, Chen, T.^, Chen, S., Feng, G., Zhang, Z.^, Li, W., Cao, N., Wang, X. J., Luo, G. Z.*^(2025). Sequence and parent-of-origin dependent m6A contribute to allele-specific gene expression. The EMBO Journal, Online ahead of print.
PMID: 40461640 DOI: 10.1038/s44318-025-00476-3

Xie, Y. Y.#^, Zhong, Z. D.#^, Chen, H. X.#^, Ren, Z. H.^, Qiu, Y. T.^, Lan, Y. L.^, Wu, F.^, Kong, J. W.^, Luo, R. J.^, Zhang, D., Liu, B. D.^, Shu, Y.^, Yin, F., Wu, J., Li, Z. G., Zhang, Z.*^, Luo, G. Z.*^ (2025). Single-molecule direct RNA sequencing reveals the shaping of epitranscriptome across multiple species. Nature Communications, 16, 5119.
PMID: 40456740 DOI: 10.1038/s41467-025-60447-4

Chai, G. S.#^, Chen, H. X.^, Ma, D. Z.^, Ren, Z. H.^, Liu, X. H.^, Zhang, Z.^, Luo, G. Z.^* (2025). Comprehensive analysis across mammalian tissues and cells decipher the underlying mechanism of m6A specificity. RNA. Online ahead of print.
PMID: 40316420 DOI: 10.1261/rna.080222.124

Xi, J. F.#^, Liu, B. D.#^, Tang, G. R.#^, Ren, Z. H.^, Chen, H. X.^, Lan, Y. L.^, Yin, F., Li, Z., Cheng, W. S., Wang, J., Chen, L., Yuan, S. C., Zhang, Z.^, Luo, G. Z.*^ (2025). m6A modification regulates cell proliferation via reprogramming the balance between glycolysis and pentose phosphate pathway. Communications Biology, 8(1): 496.
PMID: 6 DOI: 10.1038/s42003-025-07937-9

Lu, P., Deng, D., Li, X., Niu, X., Qiu, Y., Liang, Y., Liang, Y., Tang, G.^, Yuan, Z., Luo, G.^, Kennedy, S. & Wan, G.* (2025).A nuclear pore-anchored condensate enables germ granule organization and transgenerational epigenetic inheritance.Nat Struct Mol Biol (2025).
PMID: 40082670 DOI: 10.1038/s41594-025-01515-7

Li, Z. K.#, Wang, L. B.#, Wang, L. Y.#, Sun, X. H.#, Ren, Z. H.#^, Ma, S. N.#, Zhao, Y. L.#, Liu, C., Feng, G. H., Liu, T., Pan, T. S., Shan, Q. T., Xu, K., Luo, G. Z.*^, Zhou, Q.*, Li, W.* (2025). Adult bi-paternal offspring generated through direct modification of imprinted genes in mammals. Cell Stem Cell, S1934-5909(25)00005-0.
PMID: 39879989 DOI: 10.1016/j.stem.2025.01.005.

2024

Tang H.#, Shao J#^., Jiang X., Yan W., Luo G.*^, Weng X.*(2024). Detection and site-specific editing of RNA modifications. SCIENTIA SINICA Chimica.
PMID: 5 DOI: 10.1360/SSC-2024-0244

Wang Y.#, Wang Z., Chen W., Ren Z. H.^, Gao H., Dai J., Luo G. Z.^, Wu Z.*, Ji Q.*(2024). A KDPG sensor RccR governs Pseudomonas aeruginosa carbon metabolism and aminoglycoside antibiotic tolerance. Nucleic Acids Research, 52(2): 967-976.
PMID: 38096062 DOI: 10.1093/nar/gkad1201

Guo, X.#, Zhou, J.#, Yan, L.#, Liu, X., Yuan, Y., Ye, J., Zhang, Z., Chen, H., Ma, Y., Zhong, Z.^, Luo, G.^, Chen, H.* (2024). Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration. Developmental Cell, 59(22): 3008-3024. e8.
PMID: 39047737 DOI: 10.1016/j.devcel.2024.06.020

Ge, Y.#, Chen, R.#, Ling, T., Liu, B.^, Huang, J., Cheng, Y., Lin, Y., Chen, H.^, Xie, X., Xia, G., Luo, G.^, Yuan, S.*, Xu, A.*(2024). Elevated WTAP promotes hyperinflammation by increasing m 6 A modification in inflammatory disease models. The Journal of Clinical Investigation, 134(14).
PMID: 39007267 DOI: 10.1172/JCI177932

Luo, R. J.#^, Chen, H. X.^, Kong, J. W.^, Zhang, Z.^, Ayoub, N., Luo, G. Z.*^(2024). Discovery and Accurate Detection of Rare Nucleic Acid Modifications. Israel Journal of Chemistry, 64(5): e202400024.
PMID: 2 DOI: 10.1002/ijch.202400024

2023

Xu, H.#, You, H.#, Gong, J.#, Zhang, Y.#^, Du, J., Wang, X., Gu, S., Cao, N*. Wang J*. (2023) Discovery of Zidovudine as a cardiomyocyte protectant for doxorubicin-induced toxicity through high-throughput phenotypic drug screening, Fundamental Research
PMID: 0 DOI: 10.1016/j.fmre.2023.10.010

Liu, X. H.#^, Liu, Z.#, Ren, Z. H.^, Chen, H. X.^, Zhang, Y.^, Zhang, Z.*^, Cao, N.*, Luo, G. Z.*^(2023). Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation. Epigenetics & Chromatin, 16(1): 1-13.
PMID: 37568210 DOI: 10.1186/s13072-023-00506-6

Zhong, Z. D.#^, Xie, Y. Y.#^, Chen, H. X.^, Lan, Y. L.^, Liu, X. H.^, Ji, J. Y.^, Wu, F.^, Jin, L., Chen, J., Mak, D. W., Zhang, Z.*^, Luo, G. Z.*^(2023). Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing. Nature Communications, 14(1): 1906.
PMID: 37019930 DOI: 10.1038/s41467-023-37596-5

Liu, J.#, Zuo, H.#, Wang, Z.#, Wang, W., Qian, X., Xie, Y.^, Peng, D., Xie, Y., Hong, L., You, W., Lou, H., Luo, G.^, Ren, J., Shen, B., Zheng, J.*, Wang, H.*, Ju, Z.*(2023). The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K-Akt-mTOR signalling. Cell Proliferation, 2023:e13410.
PMID: 36722312 DOI: 10.1111/cpr.13410

2022

Xu, H.#, Liu, G.#, Gong, J.#, Zhang, Y.#^, Gu, S.#, Wan, Z., Yang, P., Nie, Y., Wang, Y., Huang, Z. P., Luo, G.^, Chen, Z.*, Zhang, D.*, Cao, N*. Investigating and Resolving Cardiotoxicity Induced by COVID-19 Treatments using Human Pluripotent Stem Cell-Derived Cardiomyocytes and Engineered Heart Tissues. (2022) Adv Sci (Weinh), 9(30): e2203388.
PMID: 36055796 DOI: 10.1002/advs.202203388

Chen, L. Q.#^, Zhang, Z.#^, Chen, H. X.^, Xi, J. F.^, Liu, X. H.^, Ma, D. Z.^, Zhong, Y. H.^, Ng, W. H.^, Chen, T.^, Mak, D. W., Chen, Q., Chen, Y. Q. and Luo, G. Z.*^(2022). High-precision mapping reveals rare N6-deoxyadenosine methylation in the mammalian genome. Cell Discovery, 8(1), 1-11.
PMID: 36575183 DOI: 10.1038/s41421-022-00484-1

Zhang, M.#, Zeng, Y. P., Peng, R., Dong, J., Lan, Y. L.^, Duan, S. J., Chang, Z. Y., Ren, J., Luo, G. Z.^, Liu, B., Růžička, K., Zhao, K. W., Wang, H. B.*, Jin, H. L.*(2022). N6-methyladenosine RNA modification regulates photosynthesis during photodamage in plants. Nature Communication, 13(1), 1-19.
PMID: 36460653 DOI: 10.1038/s41467-022-35146-z

Li, Y.#^, Zhi, S.#, Wu, T.#, Chen, H. X.^, Kang, R., Ma, D. Z.^, Songyang, Z., He, C.*, Liang, P*. and Luo, G. Z.*^ (2022). Systematic identification of CRISPR off-target effects by CROss-seq. Protein & Cell.
PMID: 37084235 DOI: 10.1093/procel/pwac018

Chen, HX^, Zhang, Z^, Ma, DZ^, Chen, LQ^, Luo, GZ^*. Mapping single-nucleotide m6A by m6A-REF-seq[J]. Methods, 2022, 203: 392-398.
PMID: 34174388 DOI: 10.1016/j.ymeth.2021.06.013

2021

Zhang, Z.#^, Chen, T.#^, Chen, H. X.^, Xie, Y. Y.^, Chen, L. Q.^, Zhao, Y. L.^, Liu, B. D.^, Jin, L., Zhang, W., Liu, C., Ma, D. Z.^, Chai, G. S.^, Zhang, Y.^, Zhao, W. S.^, Ng, W. H., Chen, J., Jia, G., Yang, J. and Luo, G. Z.*^ (2021). Systematic calibration of epitranscriptomic maps using a synthetic modification-free RNA library. Nat Methods 18, 1213-1222.
PMID: 34594034 DOI: 10.1038/s41592-021-01280-7

Chen, T.#^, Li, Y.#^, Ma, D.Z.^, Zhang, Z.^, Xi, J.F.^, and Luo, G.Z.* (2021). Establishment of Transposase-assisted Low-input m(6)A Sequencing Technique. J Genet Genomics.
PMID: 34474182 DOI: 10.1016/j.jgg.2021.08.007

Chen, W.#, Ren, Z.H.#^, Tang, N., Chai, G.^, Zhang, H., Zhang, Y., Ma, J., Wu, Z., Shen, X., Huang, X., Luo, G.Z.*^, Ji Q.J.* (2021). Targeted genetic screening in bacteria with a Cas12k-guided transposase. Cell Reports, 36, 109635.
PMID: 34469724 DOI: 10.1016/j.celrep.2021.109635

Zhou F#, Liu B#, Liu X, Li Y, Wang L, Huang J, Luo G*, Wang X*. The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis. Metabolites. 2021 May 6;11(5):298
PMID: 34066348 DOI: 10.3390/metabo11050298

Liu J, Gao M, He J, Wu K, Lin S, Jin L, Chen Y, Liu H, Shi J, Wang X, Chang L, Lin Y, Zhao YL, Zhang X, Zhang M, Luo GZ, Wu G, Pei D, Wang J, Bao X, Chen J. The RNA m 6 A reader YTHDC1 silences retrotransposons and guards ES cell identity. Nature. 2021 Mar;591(7849):322-326.
PMID: 33658714 DOI: 10.1038/s41586-021-03313-9

Chen X#, Zhao Q#, Zhao YL#, Chai GS, Cheng W, Zhao Z, Wang J*, Luo GZ*, Cao N*. Targeted RNA N6-Methyladenosine Demethylation Controls Cell Fate Transition in Human Pluripotent Stem Cells. Advanced Science (Weinh). 2021 Jun;8(11):e2003902
PMID: 34105279 DOI: 10.1002/advs.202003902

Wang, M.#, Xiao, Y.#, Li, Y.#^, Wang, X., Qi, S., Wang, Y., Zhao, L., Wang, K., Peng, W., Luo, G.Z.*^, Xue, X.F.*, Jia, G.F.*, Wu, L.M.* (2021). RNA m6A Modification Functions in Larval Development and Caste Differentiation in Honeybee (Apis mellifera). Cell reports 34, 108580.
PMID: 33406439 DOI: 10.1016/j.celrep.2020.108580

2020

Chen LQ#^, Zhao WS^, Luo GZ*^. Mapping and editing of nucleic acid modifications. Computational and Structural Biotechnology Journal. 18:661-667 (2020).
PMID: 32257049 DOI: 10.1016/j.csbj.2020.03.010

Du G, Xiong L, Li X, Zhuo Z, Zhuang X, Yu Z, Wu L, Xiao D, Liu Z, Jie M, Liu X^, Luo G^, Guo Z, Chen H. Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair. Developmental Cell. (20)30186-6 (2020).
PMID: 32243783 DOI: 10.1016/j.devcel.2020.03.002

Weng X, Gong J, Chen Y, Wu T, Wang F, Yang S, Yuan Y, Luo G^, Chen K, Hu L, Ma H, Wang P, Zhang QC, Zhou X, He C. Keth-seq for transcriptome-wide RNA structure mapping. Nature Chemical Biology. doi: 10.1038/s41589-019-0459-3 (2020).
PMID: 32015521 DOI: 10.1038/s41589-019-0459-3

2019

Zhang Z#^, Chen LQ^, Zhao YL^, Yang CG, Roundtree I, Zhang Z, Ren J, Xie W, He C, Luo GZ*^. Single-base mapping of m6A by an antibody-independent method. Science Advances. 5(7):eaax0250 (2019)
PMID: 31281898 DOI: 10.1126/sciadv.aax0250

Lin X#, Chai G#^, Wu Y#, Li J, Chen F, Liu J, Luo G^, Tauler J, Du J, Lin S, He C, Wang H*. RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. Nature Communications. 10: 2065 (2019)
PMID: 31061416 DOI: 10.1038/s41467-019-09865-9

Liu J#, Luo G#^, Sun J, Men L, Ye H, He C, Ren D*. METTL14 is essential for β-cell survival and insulin secretion. Biochim Biophys Acta Mol Basis Dis. 1865(9):2138-2148 (2019)
PMID: 31029827 DOI: 10.1016/j.bbadis.2019.04.011

Zhang LS#, Liu C, Ma H, Dai Q, Sun HL, Luo G^, Zhang Z, Zhang L, Hu L, Dong X, He C*. Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. Molecular Cell. 74(6):1304-1316 (2019)
PMID: 31031084 DOI: 10.1016/j.molcel.2019.03.036

Wang X#, Li Y#^, Chen W, Shi H, Eren AM, Morozov A, He C, Luo GZ*^, Pan T*. Transcriptome-wide reprogramming of N6-methyladenosine modification by the mouse microbiome. Cell Research. 29(2):167-170 (2019)
PMID: 30559439 DOI: 10.1038/s41422-018-0127-2

Chen Z#, Qi M, Shen B, Luo G^, Wu Y, Li J, Lu Z, Zheng Z, Dai Q, Wang H*. Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs. Nucleic Acids Research. 47(5):2533-2545 (2019)
PMID: 30541109 DOI: 10.1093/nar/gky1250

2018

Luo GZ#*^, Hao Z#, Luo L, Shen M, Sparvoli D, Zheng Y, Zhang Z, Weng X, Chen K, Cui Q, Turkewitz AP and He C*. N6-methyldeoxyadenosine directs nucleosome positioning in Tetrahymena DNA. Genome Biology. 19:200 (2018)
PMID: 30454035 DOI: 10.1186/s13059-018-1573-3

Yue Y, Liu J, Cui X, Cao J, Luo G^, Zhang Z, Cheng T, Gao M, Shu X, Ma H, Wang F, Wang X, Shen B, Wang Y, Feng X, He C, Liu J. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discovery. 4:10 (2018)
PMID: 29507755 DOI: 10.1038/s41421-018-0019-0

Zhu S, Beaulaurier J, Deikus G, Wu TP, Strahl M, Hao Z, Luo G^, Gregory JA, Chess A, He C, Xiao A, Sebra R, Schadt EE, Fang G. Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing. Genome Research. 28(7):1067-1078 (2018)
PMID: 29764913 DOI: 10.1101/gr.231068.117

2017

Luo GZ#^ & He C. DNA N6-methyladenine in metazoans: functional epigenetic mark or bystander? Nature Structural & Molecular Biology. 24(6):503-506 (2017)
PMID: 28586322 DOI: 10.1038/nsmb.3412

Roundtree IA, Luo GZ^, Zhang Z, Wang X, Zhou T, Cui Y, Sha J, Huang X, Guerrero L, Xie P, He E, Shen B, He C. YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs. Elife. pii: e31311 (2017)
PMID: 28984244 DOI: 10.7554/eLife.31311

Hsu PJ, Zhu Y, Ma H, Guo Y, Shi X, Liu Y, Qi M, Lu Z, Shi H, Wang J, Cheng Y, Luo G^, Dai Q, Liu M, Guo X, Sha J, Shen B, He C. Ythdc2 is an N6-methyladenosine binding protein that regulates mammalian spermatogenesis. Cell Research. 27(9):1115-1127 (2017)
PMID: 28809393 DOI: 10.1038/cr.2017.99

2016

Liu J#, Zhu Y#, Luo GZ#^, Wang X#, Yue Y, Wang X, Zong X, Chen K, Yin H, Fu Y, Han D, Wang Y, Chen D, He C. Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig. Nature Communications. 7:13052 (2016)
PMID: 27713410 DOI: 10.1038/ncomms13052

Luo GZ#^, Wang F#, Weng X, Chen K, Hao Z, Yu M, Deng X, Liu J, He C. Characterization of eukaryotic DNA N6-methyladenine by a highly sensitive restriction enzyme-assisted sequencing. Nature Communications. 7:11301 (2016)
PMID: 27079427 DOI: 10.1038/ncomms11301

Liu F, Clark W, Luo G^, Wang X, Fu Y, Wei J, Wang X, Hao Z, Dai Q, Zheng G, Ma H, Han D, Evans M, Klungland A, Pan T, He C. ALKBH1-Mediated tRNA Demethylation Regulates Translation. Cell. 167(3): 816-828 (2016)
PMID: 27745969 DOI: 10.1016/j.cell.2016.09.038

Feng G, Tong M, Xia B, Luo GZ^, Wang M, Xie D, Wan H, Zhang Y, Zhou Q, Wang XJ. Ubiquitously expressed genes participate in cell-specific functions via alternative promoter usage. EMBO Reports. 17(9):1304-13 (2016)
PMID: 27466324 DOI: 10.15252/embr.201541476

2015

Luo GZ#^, Blanco MA, Greer EL, He C, Shi Y. DNA N6-methyladenine: a new epigenetic mark in eukaryotes? Nature Reviews Molecular Cell Biology. 16(12):705-10 (2015)
PMID: 26507168 DOI: 10.1038/nrm4076

Fu Y#, Luo GZ#^, Chen K, Deng X, Yu M, Han D, Hao Z, Liu J, Lu X, Doré LC, Weng X, Ji Q, Mets L, He C. N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas. Cell. 161(4):879-92 (2015)
PMID: 25936837 DOI: 10.1016/j.cell.2015.04.010

Chen K, Luo GZ^, He C. High-Resolution Mapping of N⁶-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy. Methods Enzymol. 560:161-85 (2015)
PMID: 26253971 DOI: 10.1016/bs.mie.2015.03.012

Shuai L, Wang Y, Dong M, Wang X, Sang L, Wang M, Wan H, Luo G^, Gu T, Yuan Y, Feng C, Teng F, Li W, Liu X, Li T, Wang L, Wang XJ, Zhao XY, Zhou Q. Durable pluripotency and haploidy in epiblast stem cells derived from haploid embryonic stem cells in vitro. J Mol Cell Biol. 7(4):326-37 (2015)
PMID: 26169120 DOI: 10.1093/jmcb/mjv044

Deng X, Chen K, Luo GZ^, Weng X, Ji Q, Zhou T, He C. Widespread occurrence of N6-methyladenosine in bacterial mRNA. Nucleic Acids Research. 43(13):6557-67 (2015)
PMID: 26068471 DOI: 10.1093/nar/gkv596

Chen K, Lu Z, Wang X, Fu Y, Luo GZ^, Liu N, Han D, Dominissini D, Dai Q, Pan T and He C. High-Resolution N6-Methyladenosine (m6A) Map Using Photo-Crosslinking-Assisted m6A Sequencing. Angew Chem Int Ed Engl. 54(5):1587-90 (2015)
PMID: 25491922 DOI: 10.1002/anie.201410647

2014

Luo GZ#^, MacQueen A#, Zheng G#, Duan H, Dore LC, Lu Z, Liu J, Chen K, Jia G*, Bergelson J*, He C*. Unique features of the m6A methylome in Arabidopsis thaliana. Nature Communications. 5:5630 (2014)
PMID: 25430002 DOI: 10.1038/ncomms6630

Luo GZ#^, Yang W, Ma YK, Wang XJ. ISRNA: an integrative online toolkit for short reads from high-throughput sequencing data. Bioinformatics. 30(3):434-6 (2014)
PMID: 24300438 DOI: 10.1093/bioinformatics/btt678

Li W, Li X, Li T, Jiang MG, Wan H, Luo GZ^, Feng C, Cui X, Teng F, Yuan Y, Zhou Q, Gu Q, Shuai L, Sha J, Xiao Y, Wang L, Liu Z, Wang XJ, Zhao XY, Zhou Q. Genetic modification and screening in rat using haploid embryonic stem cells. Cell Stem Cell. 14(3):404-14 (2014)
PMID: 24360884 DOI: 10.1016/j.stem.2013.11.016

Fu L, Shi Z, Luo G^, Tu W, Wang X, Fang Z, Li X. Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3' untranslated region. Mol Brain. 7:71 (2014)
PMID: 25269856 DOI: 10.1186/s13041-014-0071-0

2013

Shi Z#, Luo G^, Fu L, Fang Z, Wang X, Li X. miR-9 and miR-140-5p target FoxP2 and are regulated as a function of the social context of singing behavior in zebra finches. J Neurosci. 33(42):16510-21 (2013)
PMID: 24133256 DOI: 10.1523/JNEUROSCI.0838-13.2013

Wan H, He Z, Dong M, Gu T, Luo GZ^, Teng F, Xia B, Li W, Feng C, Li X, Li T, Shuai L, Fu R, Wang L, Wang XJ, Zhao XY, Zhou Q. Parthenogenetic haploid embryonic stem cells produce fertile mice. Cell Research. 23(11):1330-3 (2013)
PMID: 24018377 DOI: 10.1038/cr.2013.126

Zhang Y, Teng F, Luo GZ^, Wang M, Tong M, Zhao X, Wang L, Wang XJ, Zhou Q. MicroRNA-323-3p regulates the activity of polycomb repressive complex 2 (PRC2) via targeting the mRNA of embryonic ectoderm development (Eed) gene in mouse embryonic stem cells. J Biol Chem. 288(33):23659-65 (2013)
PMID: 23821546 DOI: 10.1074/jbc.M113.475608

Li RC, Tao J, Guo YB, Wu HD, Liu RF, Bai Y, Lv ZZ, Luo GZ^, Li LL, Wang M, Yang HQ, Gao W, Han QD, Zhang YY, Wang XJ, Xu M, Wang SQ. In Vivo Suppression of MiR-24 Prevents the Transition toward Decompensated Hypertrophy in Aortic-constricted Mice. Circ Res. 112(4):601-5 (2013)
PMID: 23307820 DOI: 10.1161/CIRCRESAHA.112.300806

Han J, Chen L, Luo G^, Dai B, Wang X, Dai J. Three-dimensional culture may promote cell reprogramming. Organogenesis. 9(2):118-20 (2013)
PMID: 23820263 DOI: 10.4161/org.24708

Liu X, Zhang Y, Tong M, Liu XY, Luo GZ^, Xie DF, Ren SF, Bai DH, Wang L, Zhou Q, Wang XJ. Identification of a small molecule 1,4-bis-[4-(3-phenoxy-propoxy)-but-2-ynyl]-piperazine as a novel inhibitor of the transcription factor p53. Acta Pharmacol Sin. 34(6):805-10 (2013)
PMID: 23736005 DOI: 10.1038/aps.2013.61

2012

Luo GZ#^, Hafner M#, Shi Z, Brown M, Feng GH, Tuschl T, Wang XJ*, Li X*. Genome-wide annotation and analysis of zebra finch microRNA repertoire reveal sex-biased expression. BMC Genomics. 13:727 (2012)
PMID: 23268654 DOI: 10.1186/1471-2164-13-727

Li W, Shuai L, Wan H, Dong M, Wang M, Sang L, Feng C, Luo GZ^, Li T, Li X, Wang L, Zheng QY, Sheng C, Wu HJ, Liu Z, Liu L, Wang L, Wang XJ, Zhao XY, Zhou Q. Androgenetic haploid embryonic stem cells produce live transgenic mice. Nature. 490(7420):407-11 (2012)
PMID: 22891046 DOI: 10.1161/CIRCRESAHA.112.277418

Xu M, Wu HD, Li RC, Zhang HB, Wang M, Tao J, Feng XH, Guo YB, Li SF, Lai ST, Zhou P, Li LL, Yang HQ, Luo GZ^, Bai Y, Xi JJ, Gao W, Han QD, Zhang YY, Wang XJ, Meng X, Wang SQ. Mir-24 Regulates Junctophilin-2 Expression in Cardiomyocytes. Circ Res. 111(7):837-41 (2012)
PMID: 22891046 DOI: 10.1161/CIRCRESAHA.112.277418

Zhang C, Xu Y, Guo S, Zhu J, Huan Q, Liu H, Wang L, Luo G^, Wang X, Chong K. Dynamics of brassinosteroid response modulated by negative regulator LIC in rice. PLoS Genet. 8(4):e1002686 (2012)
PMID: 22570626 DOI: 10.1371/journal.pgen.1002686

Du Y, Gao C, Liu Z, Wang L, Liu B, He F, Zhang T, Wang Y, Wang X, Xu M, Luo GZ^, Zhu Y, Xu Q, Wang X, Kong W. Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification. Arterioscler Thromb Vasc Biol. 32(11):2580-8 (2012)
PMID: 22995515 DOI: 10.1161/ATVBAHA.112.300206

2010

Liu L#, Luo GZ#^, Yang W#, Zhao X#, Zheng Q, Lv Z, Li W, Wu HJ, Wang L, Wang XJ, Zhou Q. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. Journal of Biological Chemistry. 285(25):19483-90 (2010)
PMID: 20382743 DOI: 10.1074/jbc.M110.131995

2009

Zhou Y, Li S, Qian Q, Zeng D, Zhang M, Guo L, Liu X, Zhang B, Deng L, Liu X, Luo G^, Wang X, Li J. BC10, a DUF266-containing and Golgi-located type II membrane protein, is required for cell-wall biosynthesis in rice (Oryza sativa L.). Plant J. 57(3):446-62 (2009)
PMID: 18939965 DOI: 10.1111/j.1365-313X.2008.03703.x

Liu X, Luo G^, Bai X, Wang XJ. Bioinformatic analysis of microRNA biogenesis and function related proteins in eleven animal genomes. J Genet Genomics. 36(10):591-601 (2009)
PMID: 19840757 DOI: 10.1016/S1673-8527(08)60151-4